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Cholera gives up its secrets

点击量:   时间:2019-03-06 02:09:04

THE entire genome of the microbe that causes cholera has been sequenced. The bacterium Vibrio cholerae lives in water and often strikes down people in the aftermath of wars and disasters, such as the recent floods in Mozambique, when drinking water becomes tainted. But its sequence suggests that it didn’t always have a taste for humans. It appears that an ancient, non-virulent ancestor acquired an extra chromosome, and many of the genes that allow cholera to attack people are found on this (Nature, vol 406,